The NanoSight NS300 provides rapid and automated analysis of the size distribution and concentration of all types of nanoparticles in suspension in the size range of 10-2000nm (depending on material) and addresses the needs of a wide variety of applications including protein aggregation, exosome and macrovesicle research, drug delivery systems and characterization of materials.

This instrument provides multi-faceted analysis that includes a motorized filter wheel, as well as a rheology feature that can measure viscosity in the range 0-5 centipoise. With a footprint measuring just 40cm long by 25cm wide, the NS300 is packed with NanoSight’s latest developments. It comes complete with a high-sensitivity CMOS camera, temperature control, and a choice of laser block.

A new top plate and laser module block are removable to enable easy cleaning and assembly. The top plate comes with a replaceable sample chamber designed with a special stem to enable removal without having to handle the sensitive sample area. It has very easy and sophisticated Nanoparticle Tracking Analysis (NTA) software.

Additional information including manual and video instruction can be found here.


  • Protein aggregation studies 
  • Fluorescently labeled particles
  • Exosomes and microvesicles
  • Pharmaceutical nanoparticles-liposomes

 NS300 workflow

 1. Load a sample* into the chamber on the instrument

2. Optimise the image

  • Concentration
  • Beam position
  • Focus
  • Camera settings

3. Make a measurement

4. Process videos - Set in the workflow by NTA software

5. Results and exports

*It is recommended that “size standard beads” be used as an initial sample type.