Qiaozhu SuAssistant Professor
2002 – 2007, Graduate Research Assistant, McGill University, Canada
2007 – 2012, Postdoctoral Associate, University of Toronto, Canada
2012-present, Assistant Professor, Department of Nutrition and Health Sciences, University of Nebraska-Lincoln (UNL)
I have always been fascinated by the biological processes underlying the metabolic system. During my Ph.D. and postdoctoral studies in medical school, the rapid and devastating onset of metabolic syndrome that develops in patients with nutrient surplus completely captured my attention. Understanding how nutritional signaling and different dietary compositions, particularly lipids, are causally linked to the development of metabolic diseases, such as obesity and diabetes, continues to provide the foundation for my research career.
Areas of Expertise: An important goal of my laboratory is to investigate the associations between cellular stress signaling, lipid/lipoprotein metabolism and the molecular mechanisms in the development metabolic syndrome, such as obesity and diabetes. My research program concerns three main areas:
- The association between microRNAs induced by lipogenic diets and insulin resistance.
- The mechanisms underlie the aberrant activation of hepatic de novo lipogenesis in insulin resistant animal models that are mediated by the transcription factors, SREBP and CREBH, and their association with the insulin signaling molecules, Insig-1 and Insig-2.
- The mechanisms responsible for overproduction of very low density lipoprotein (VLDL) in subjects with obesity and diabetes.
Students in my laboratory will receive a broad and comprehensive training to discover novel link between nutrient surplus, lipid/lipoprotein metabolism and cellular stress signaling in the onset of chronic metabolic disorders. Each trainee will have an independent project and also be involved in topic-common projects in the laboratory to broaden their knowledge of biomedical sciences.
(Su lab is accepting applications for the UCARE program at UNL)