Chandirasegaran Massilamany

Chandirasegaran Massilamany, DVM, MVSc, PhD NPOD Mentors and Members


Research Assistant Professor

School of Veterinary Medicine & Biomedical Sciences
UNL
VBS 120
Lincoln NE 68583-0905

Phone: 402.472.8537  |  Email: cmassilamany@unl.edu

External Website:
https://directory.unl.edu/people/s-cmassil1

Research Interests: 

I have used various  mouse models  of autoimmunity to address  the role ofT cells in the causation  of immune-mediated damage triggered  by microbes.  These include  experimental autoimmune encephalomyelitis for multiple  sclerosis, experimental autoimmune and viral myocarditis for dilated  cardiomyopathy/heart failure,  and experimental autoimmune uveoretinitis for uveitis  in humans.   I am now developing the T cell receptor  transgenic mouse for cardiac  myosin  that permits  us to dissect  the immune mechanisms of myocardial  infarction/cardiomyopathy leading  to heart failure,  and also creating  mutant viruses  of Coxsackievirus as vaccine  candidates to prevent  heart disease  and diabetes.