External Website:
https://www.unmc.edu/eppley/about/faculty/lewis.html

The Lewis Lab focuses on the role of molecular scaffolds KSR1 and KSR2 in the regulation of Ras-driven tumorigenesis (KSR1) and organismal energy balance (KSR2). Using genetically-modified mice and cell lines, the lab is defining novel signal transduction pathways in tumors that may prove therapeutically vulnerable, and identifying physiological mechanisms critical for normal energy expenditure that appear altered in obesity.