Robert E. Lewis, PhD Internal Advisory Committee


Professor and Program Leader, Fred & Pamela Buffett Cancer Center

Eppley Institute for Research in Cancer and Allied Diseases
University of Nebraska Medical Center
Eppley Institute for Research in Cancer
University of Nebraska Medical Center, LTC 12706
987696 Nebraska Medical Center
Omaha, NE 68198-7696

Phone: 402.559.8290  |  Email:

External Website:

The Lewis Lab focuses on the role of molecular scaffolds KSR1 and KSR2 in the regulation of Ras-driven tumorigenesis (KSR1) and organismal energy balance (KSR2). Using genetically-modified mice and cell lines, the lab is defining novel signal transduction pathways in tumors that may prove therapeutically vulnerable, and identifying physiological mechanisms critical for normal energy expenditure that appear altered in obesity.